Early Identification of Mild Cognitive Impairment in Person with Cancer Undergoing Chemotherapy: Associations with Anxiety, Sleep Disturbance and Depression.

Influence of Sleep Quality on Cognitive Performance Addressing the second objective, a moderate and highly significant negative correlation was found between sleep quality (PSQI) and cognitive performance (CFRT) (ρ = −0.583; p < 0.001), indicating that poorer sleep was associated with lower cognitive functioning.

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Among the predictors, both sleep quality (β = −0.471; p < 0.001) and age (β = −0.233; p < 0.01) emerged as significant negative predictors, whereas anxiety/depression did not reach statistical significance in the multivariate model (β = −0.072; p = 0.173), suggesting that its effect may be mediated by age or sleep quality.

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