The Effect of Splenectomy on Postoperative Morbidity and Survival in Patients with Peritoneal Carcinomatosis.

J Clin Med · 2025 · PMC12653215 · PMID 41303257

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.3690

boldest claim

The sentences

highly significantp < 0.001actually significant

Splenectomy indication emerged as a highly significant independent predictor of DFS (overall p < 0.001).

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borderline significancep = 0.050actually significant

Complete cytoreduction score showed borderline significance in univariate analysis ( p = 0.050).

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did not reach statistical significancep = 0.369not close (p > 0.1)

However, when examined by specific indication, peritoneal implant splenectomy demonstrated a borderline association with increased mortality risk (OR = 4.505, 95% CI: 0.939–21.620, p = 0.060), though this did not reach statistical significance. Hilar invasion splenectomy showed no association with OS (OR = 0.448, 95% CI: 0.078–2.582, p = 0.369), and iatrogenic splenectomy could not be estimated due to zero events.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.