Association of qEEG TAR and TBR During Eyes-Open and Eyes-Closed with Plasma Oligomeric Amyloid-β Levels in an Aging Population.

J Clin Med · 2025 · PMC12653316 · PMID 41303105

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1100

boldest claim

The sentences

a trend toward significancep = 0.05actually significant

In the unadjusted model, higher MDS-OAβ levels were significantly associated with a lower TBR in the frontal (β = −0.04, p = 0.02), central (β = −0.06, p = 0.02), and temporal lobes (β = −0.06, p = 0.01), with a trend toward significance in the parietal lobe (β = −0.05, p = 0.05).

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borderline significancep = 0.06so close (0.05 < p ≤ 0.1)

The parietal lobe demonstrated the strongest association in the adjusted model (β = −0.05, p = 0.06, borderline significance), while the occipital lobe retained a negative but nonsignificant trend (β = −0.05, p = 0.09).

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did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Occipital TBR also exhibited weak negative correlations, though these did not reach statistical significance (EO: r = −0.06, p = 0.08; EC: r = −0.06, p = 0.07).

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a nonsignificant trendp = 0.11not close (p > 0.1)

The frontal lobe exhibited a nonsignificant trend (β = −0.03, p = 0.11).

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