Association Between Obstructive Sleep Apnea and Cardiovascular Risk: A Systematic Review and Meta-Analysis of Prospective Cohort Studies.

Medicina (Kaunas) · 2025 · PMC12654527 · PMID 41303825

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did not reach statistical significanceno p-value reported

It is noteworthy that the pooled estimate for mild OSA (HR 1.21, 95% CI 0.98–1.50) did not reach statistical significance, suggesting that cardiovascular risk becomes clinically relevant mainly in moderate-to-severe OSA.

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