Microbial Interventions for Inflammatory Skin Diseases: A Systematic Review and Meta-Analysis of Atopic Dermatitis and Psoriasis.

Microorganisms · 2025 · PMC12654813 · PMID 41304102

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0800

boldest claim

The sentences

a favorable trendp = 0.06so close (0.05 < p ≤ 0.1)

Although the percentage of patients achieving ≥75% reduction in PASI showed a favorable trend in the probiotic group (33.57% vs. 23.61%), this difference did not reach statistical significance (RR 1.40; 95% CI: 0.98–1.98; p = 0.06).

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did not reach statistical significancep = 0.080so close (0.05 < p ≤ 0.1)

Egger’s test did not reach statistical significance ( p = 0.080); however, the borderline p -value may suggest a trend towards asymmetry, a finding that must be interpreted with significant caution given the limited power of the test with only five included studies. 4.

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