Cytokine and Metabolomic Signatures of Mepolizumab Response Across Upper and Lower Airway Compartments in Severe Eosinophilic Asthma: An Exploratory Analysis.

Pharmaceuticals (Basel) · 2025 · PMC12655059 · PMID 41304949

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.1280

boldest claim

The sentences

a trend toward significancep = 0.056so close (0.05 < p ≤ 0.1)

T 0 ), and only a trend toward significance was observed at T 12 ( p = 0.056 vs.

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did not reach statistical significancep = 0.128not close (p > 0.1)

Although FEV 1 % showed an increase over time, it did not reach statistical significance at T 6 ( p = 0.128 vs.

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