An Investigational Study on the Role of ADME Agents' Genetic Variation on DD217 Pharmacokinetics and Safety Profile.

Pharmaceuticals (Basel) · 2025 · PMC12655527 · PMID 41304863

Europe PMC DOI

hedged sentence

0.0693

closest p · 1.4× alpha

0.0693

boldest claim

The sentences

did not reach statistical significancep = 0.06926so close (0.05 < p ≤ 0.1)

For AUC last and C max , only a trend toward higher values was observed in IM/PM carriers, which did not reach statistical significance ( p = 0.06926 and p = 0.1259, respectively).

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