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Efficiency of Calcium Fructoborate-Loaded Novel Natural Niosomes Compared to Traditional Liposomes and Niosomes in Rat Ischemia-Reperfusion Injury Model.

Pharmaceutics · 2025 · PMC12655740 · PMID 41304772

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In summary, our study demonstrated that the NN nanoparticle method, produced entirely through natural processes using squalene and saponin, enhanced the efficacy of the CF active ingredient, although some histological improvements, such as reduced tubular dilation and epithelial thinning, did not reach statistical significance.

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