Genomic Analysis of Glycosyltransferases Responsible for Galactose-α-1,3-Galactose Epitopes in <i>Streptococcus pneumoniae</i>: Implications for Broadly Protective Vaccination Strategy.

Vaccines (Basel) · 2025 · PMC12656782 · PMID 41295521

Europe PMC DOI

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did not reach statistical significanceno p-value reported

904 in WT), this difference did not reach statistical significance.

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highly significantno p-value reported

This finding is highly significant as it shifts the paradigm from live bacteria to a defined vaccine preparation, highlighting the critical role of anti-Gal antibodies in the immunogenicity of carbohydrate-based vaccines.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Genomic Analysis of Glycosyltransferases Responsible for Galactose-α-1,3-Galactose Epitopes in &lt;i&gt;Streptococcus pneumoniae&lt;/i&gt;: Implications for Broadly Protective Vaccination Strategy.

The sentences

Genomic Analysis of Glycosyltransferases Responsible for Galactose-α-1,3-Galactose Epitopes in <i>Streptococcus pneumoniae</i>: Implications for Broadly Protective Vaccination Strategy.