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Comparative efficacy and safety of symptomatic therapy and disease-modifying therapy for Alzheimer's disease: a systematic review and network meta-analysis.

Front Neurosci · 2025 · PMC12657434 · PMID 41322352

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While donanemab demonstrated superiority over placebo in the composite endpoint integrating measures of cognition and activities of daily living, secondary outcomes did not reach statistical significance.

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