Defining the role of β-cell IRE1α/XBP1 pathway and its gene regulatory network components in non-obese diabetic mice.

Nat Commun · 2025 · PMC12657516 · PMID 41298424

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showed a trendno p-value reported

This phenotype was reminiscent of IRE1α β-/- mice where the percentage of CD4 + T cells showed a trend towards declining, and the percentage of CD8 + T cells was significantly diminished.

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