High-Plex Digital Spatial Profiling Identified Prolactin-Induced Protein mRNA Associated With Response and Survival of Everolimus and Letrozole Treatment for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer.

In the CD45+ zone, a trend toward higher expression was observed but did not reach statistical significance ( p = 0.096, Figure 7B ).

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A p ‐value less than 0.05 was considered statistically significant, and a p ‐value less than 0.1 was considered to indicate a tendency toward significance, both of which regarded as false discovery rate (FDR) under appropriate contexts.

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