Further conditional analysis of the Apo L1 signal, using variants that differ in AF between AFR and EUR reference populations by at least 0.1 and have nominally significant associations with Apo L1 concentrations in GWASs from the JHS (rather than using variants reported in the literature), identified five JHS-identified variants that jointly attenuated the local ancestry signal ( Table S4 ).
← all excerpts
Admixture-mapping analysis reveals genetic determinants of the human plasma proteome.
1
—
—