The AML cellular state space unveils NPM1 immune evasion subtypes with distinct clinical outcomes.

Nat Commun · 2025 · PMC12658069 · PMID 41290664

Europe PMC DOI

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0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

showed a trendP = 0.051so close (0.05 < p ≤ 0.1)

This showed a trend towards a higher proportion of CD8 naive cells in both scRNA-seq and flow cytometry data ( P = 0.051 and P = 0.065), suggesting microenvironmental differences between the two NPM1 classes affecting the T cell composition already at diagnosis.

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