Edaravone attenuates doxorubicin-induced oral mucosal injury via modulation of oxidative stress, inflammatory signaling, and the SIRT1/TLR4/NF-kB/ACE2 axis in rats.

BMC Oral Health · 2025 · PMC12659584 · PMID 41299536

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0970

boldest claim

The sentences

highly significantp < 0.001actually significant

One-way ANOVA demonstrated a highly significant group effect on SOD activity (F = 32.899, p < 0.001).

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did not reach statistical significancep = 0.097so close (0.05 < p ≤ 0.1)

DOX), although the difference between the two edaravone doses did not reach statistical significance ( p = 0.097) (Fig. 5 ).

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