The Effectiveness of AI Chatbots in Alleviating Mental Distress and Promoting Health Behaviors Among Adolescents and Young Adults: Systematic Review and Meta-Analysis.

J Med Internet Res · 2025 · PMC12661615 · PMID 41313175

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

failed to reach statistical significanceno p-value reported

Generative chatbots, while showing a potentially large effect, exhibited a wide CI and failed to reach statistical significance (Table S4 in Multimedia Appendix 1 ).

also in 6,035 other papers

a positive trendno p-value reported

Self-Efficacy Six trials were included in the meta-analysis to evaluate the pooled effect of chatbot interventions on self-efficacy outcomes, resulting in a positive trend effect favoring the experimental group but no statistically significant difference obtained (SMD 0.14, 95% CI −0.14 to 0.41; P =.33) (Figure S9 in Multimedia Appendix 1 ).

also in 11,005 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.