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Metabolic reprogramming in Fanconi anemia: Evidence of compromised glucose oxidation, enhanced ketogenesis, and metabolic inflexibility.

Sci Adv · 2025 · PMC12662205 · PMID 41313766

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Levels of C-peptide, which is cosecreted with insulin in equimolar amounts and is a surrogate marker of insulin secretion ( 39 , 41 ), showed a shifted peak in individuals with FA compared to controls but the difference did not reach statistical significance ( Fig. 9F ).

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