Dynamic assessment of proliferation to guide response-adapted therapy in the setting of neoadjuvant chemotherapy in ER+/HER2- breast cancer.

Transl Oncol · 2026 · PMC12663844 · PMID 41242143

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a borderline significant trendno p-value reported

Patients with low-proliferative C2 tumors, as determined by SSP-Ki67, showed a borderline significant trend toward improved prognosis in univariable analysis (SSP-Ki67: HR = 0.104, 95 % CI: 0.011–1.006, Log-rank p = 0.017; Fig. 5 ).

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