“a borderline significant trend”

1 Mean difference −0.62 × 10 − 3 (95% CI −1.25 to 0.01) × 10 − 3 , p = 0.06, indicating a borderline significant trend favoring darbepoetin; Fig. 2 Mean difference −0.83 × 10 − 3 (95% CI −1.46 to −0.19) × 10 − 3 , p = 0.01, demonstrating a statistically significant advantage for darbepoetin Fig. 3 Mean difference −1.45 × 10 − 3 (95% CI −2.06 to −0.83) × 10 − 3 , p < 0.00001, indicating a highly significant superiority of darbepoetin Collectively, these findings suggest that, under most study conditions, darbepoetin is likely to be more effective than short-acting epoetin in achieving or maintaining target hemoglobin concentrations.

Moreover, our results could be conservative because the 131 threatened species in our study show a borderline significant trend towards having more missing traits than non-threatened species (Kruskal–Wallis test: p = 0.04, χ 2 = 19.96, df = 2; Supplementary Methods .

A borderline significant trend toward increased risk was observed for schizophrenia (hazard ratio [HR] = 1.82, 95% confidence interval [CI] = 1.01–3.27, P = .0410) and suicide-related outcomes (HR = 1.38, 95% CI = 0.76–2.51, P = .2858); however, these associations did not remain significant after correction for multiple comparisons ( Figure 2 ).

For Confident , there was only a borderline significant trend ( p =0.049).

Finally, a non-significant trend for zinc deficiency was found in PPI users (81.2 ± 13.9 versus 87.0 ± 12.7, p = 0.08) and also a borderline significant trend for lower sodium levels in PPI users (139.8 ± 3.8 versus 141.8 ± 4.6, p = 0.05).

A borderline significant trend toward increased SAE risk was observed (OR = 3.36, P = 0.05).

Meanwhile, studies with higher proportions of patients with AFP > 400 showed a borderline significant trend toward elevated HRs for PFS ( p = 0.05).

While the weighted median method suggested a borderline significant trend ( p < 0.05), MR-Egger analysis did not confirm this association.

The sensitivity analysis, including studies where the effect size was approximated from median and interquartile range, showed a borderline significant trend towards higher image quality for DLR (summary effect size of 1.38, 95% confidence interval 0.00–2.04, p = 0.05, df = 32).

In contrast, heavy physical labor showed only a borderline significant trend ( P = 0.05, OR = 6.90), but its substantial effect size warranted inclusion in the model, suggesting a potential clinical relevance that merits further investigation.

Length of hospital stay showed a borderline significant trend favoring PPF (11.00 ± 6.99 vs. 16.27 ± 13.03 days, p = 0.05).

For EPA + DHA intake, the association approached but did not reach statistical significance for all-cause mortality ( P = 0.055), while showing a borderline significant trend for cardiovascular mortality ( P = 0.050), as depicted in Fig.

Node count showed a borderline significant trend (−2.59/μm, p = 0.051), while BD was unaffected (−0.0026 mm − 2 /μm, p = 0.498).

There were no significant between group differences in total distance at any displacement, but the Avoider vs Non‐Avoider group comparison at day 5 showed a borderline significant trend ( p = 0.0526) (Figure S6C ).

Interestingly, we found a borderline significant trend ( p = 0.053) in the MRD-negative group, where patients with a higher MaxΔVAF (suggesting a larger drop from a potentially higher preoperative VAF) paradoxically showed a trend towards worse DFS (Fig. 3 A).

Aluminum foil and utensil usage were minimal, with most participants never using them, although aluminum foil showed a borderline significant trend (χ2 = 16.62, P < 0.055).

Left common carotid stenosis demonstrated a borderline significant trend ( p = 0.057), with highest prevalence in harmful drinking group (7.6%).

For persons without experience with serious mental illness personally or knowing others versus those with such experience, the total impact score for the workshop had a borderline significant trend towards more impact for those with experience (Z(1) = -1.91, p = 0.057), but no significant difference for opera total impact score (Z(1) = -1.28, p = 0.199).

Publication year showed a borderline significant trend toward lower relapse rates in more recent studies (β = −0.31, 95% CI: −0.62 to 0.01, p -value = 0.058), which could reflect improvements in patient selection or withdrawal protocols.

In the Kaplan-Meier plot comparing the groups with 1:1 matching, a borderline significant trend ( P = 0.059) can be seen, with the non-users having an earlier dementia diagnosis rate or a higher AD susceptibility than the drug user group ( Figure 4A ).

Regarding the distribution of Candida species, there was a borderline significant trend of more patients with C. tropicalis in the non-survivor group than in the survivor group (48.3% vs. 27.5%, p = 0.060).

When tested for interaction effects, there was a borderline significant trend of negative interaction observed between schizophrenia diagnosis and KL-VS Het+ on attention z -scores; β = −.56, P = .060 ( Table 2 ).

The ADR showed a borderline significant trend of decline between cataract surgeries ( P = .06), compared to baseline with significant recovery ( P = .033) after the second cataract surgery to near baseline ( Figure ).

LSM values maintain a significant negative association with the ideal LS7 category even after adjustment (−0.79 kPa, p=0.038), while the intermediate category showed a borderline significant trend (−0.68 kPa, p=0.061).

Meanwhile, low IC GITR expression corresponded to an increased OS with a borderline significant trend ( p = 0.064).