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Asparagine endopeptidase (AEP) inhibitor formulation via zein-based nanoparticle improves the therapeutic efficacy toward Alzheimer's disease.

Neurotherapeutics · 2025 · PMC12664493 · PMID 40816999

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Quantification with Aβ ELISA indicated that Aβ42 levels were significantly reduced by 11a-isopropyl, while the other two drugs showed a reduction trend that did not reach statistical significance ( Fig. 6 E).

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