Characterisation and impact of intratumoural stroma in melanoma and carcinoma brain metastases.

J Pathol Clin Res · 2026 · PMC12664527 · PMID 41317317

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

borderline significancep = 0.050actually significant

In the univariate Kaplan–Meier analysis, the following factors were significantly associated with survival: age ( p < 0.001), sex ( p < 0.001), location of the BM ( p = 0.006), primary organ of the metastasis ( p = 0.019) and, with borderline significance, the histological subtype ( p = 0.050).

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did not reach statistical significancep = 0.056so close (0.05 < p ≤ 0.1)

a trend toward significanceno p-value reported

Stratification by IDS status showed a trend toward significance but did not reach statistical significance for survival differences ( p = 0.056).

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