Inhibition of microglial glutaminase alleviates chronic stress-induced neurobehavioral and cognitive deficits.

Analysis of snRNA-seq data ( GSE144136 ) from post-mortem dorsolateral PFC (BA9) tissue of MDD subjects who died by suicide [ 39 ] showed a strong trend toward a higher proportion of GLS1 -expressing microglia compared to healthy controls ( Fig. 1 A– Supplementary Table 1 ).

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