Barely Significant
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Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.

Front Genet · 2025 · PMC12665383 · PMID 41328434

1
hedged sentence
0.0210
closest p · 0.4× alpha
0.0210
boldest claim

The sentences

nominally significantp ≈ 0.021actually significant
MR estimates were directionally consistent across methods, with nominally significant associations under IVW (OR ≈ 1.001; 95% CI ∼1.000–1.002; p ≈ 0.021) and weighted median (OR ≈ 1.0009; 95% CI ∼1.0002–1.0017; p ≈ 0.011), whereas MR-Egger and weighted mode were not significant ( Figure 3B , Supplementary File 2 ).

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