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DL-3-n-Butylphthalide Protects Mitochondria Against Ischemia/Hypoxia Damage via Suppressing GCN5L1-Mediated Drp1 Acetylation in Neurons and Mouse Brains.

CNS Neurosci Ther · 2025 · PMC12665616 · PMID 41320852

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As shown in Figure S1C–E , mitochondrial dysfunction (cellular ATP depletion, mPTP opening) occurred as early as 3 h post‐OGD, while cell apoptosis was only rarely detected at this time, and the apoptotic difference did not reach statistical significance until 4 h post‐OGD compared with the untreated control.

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