Recognition, prevention, and management of adverse events associated with asparaginase/ pegaspargase treatment of acute lymphoblastic leukemia in adults: consensus of an expert panel.

Haematologica · 2025 · PMC12666278 · PMID 40109190

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hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

did not reach statistical significanceP =0.055so close (0.05 < p ≤ 0.1)

26 Although these results did not reach statistical significance ( P =0.055 for hyperbilirubinemia; P =0.065 for transaminase elevation), they did suggest a connection between higher BMI and increased hepatotoxicity. 26 This finding is supported by an analysis of patients treated in the GMALL study (N=1,226), in which patients with BMI >30 kg/m2 experienced sign

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