Development of an over-gap droplet digital PCR assay and evaluation of serum HBcrAg/qAnti-HBc as noninvasive markers for intrahepatic replication-competent HBV DNA in chronic hepatitis B patients with HBsAg loss.

Emerg Microbes Infect · 2025 · PMC12667311 · PMID 41221629

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did not reach statistical significanceno p-value reported

Additionally, a comparison of the three indicators revealed that the serum HBcrAg, qAnti-HBc, and liver tissue repDNA levels were generally greater in the CHB group than in the LC group, although the differences did not reach statistical significance.

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