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Developmental programming: Differing impact of prenatal testosterone and prenatal bisphenol-A -treatment on hepatic methylome in female sheep.

Mol Cell Endocrinol · 2025 · PMC12668269 · PMID 40914344

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Although the reduction in gene expression for these genes did not reach statistical significance ( Saadat et al., 2022 ), it is possible that the hypermethylation led to inefficient transcription initiation or altered mRNA processing, ultimately resulting in lower levels of protein expression for these genes.

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