Barely Significant
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Rectal Indomethacin in Preventing Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: An Updated Meta-Analysis with Trial Sequential Analysis.

Dig Dis · 2025 · PMC12668724 · PMID 40911498

1
hedged sentence
0.1210
closest p · 2.4× alpha
0.1210
boldest claim

The sentences

did not reach statistical significancep = 0.121not close (p > 0.1)
Similarly, stratification by baseline patient risk showed a more pronounced benefit in high-risk patients (RR: 0.47, 95% CI: 0.30–0.75) compared to average-risk individuals (RR: 0.66, 95% CI: 0.52–0.84), though subgroup differences did not reach statistical significance (Q = 2.41, p = 0.121) (online suppl.

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