The unfolded protein response in progeria arteries originates from non-endothelial cell types.

Life Sci Alliance · 2026 · PMC12670121 · PMID 41326174

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a clear trendno p-value reported

We tested the expression of UPR genes in whole aorta lysates of Lmna G609G/+ mice by qRT-PCR and found that most genes were either significantly up-regulated or showed a clear trend for up-regulation compared with Lmna +/+ control samples ( Fig 7B ).

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