Phenotypic variability in early-onset dementia segregating with a novel APP (p.I718M) variant.

Alzheimers Res Ther · 2025 · PMC12670831 · PMID 41327373

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hedged sentence

0.1040

closest p · 2.1× alpha

0.1040

boldest claim

The sentences

did not reach statistical significancep = 0.104not close (p > 0.1)

There was a trend towards increased CSF t-tau and NfL in APP p.I718M MC, though it did not reach statistical significance ( p = 0.104).

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