Yes-associated protein regulates autophagy to restore skin barrier function in atopic dermatitis.

Front Immunol · 2025 · PMC12672505 · PMID 41346593

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did not reach statistical significanceno p-value reported

Although YAP and LC3 co-localization also increased, the difference did not reach statistical significance.

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an increasing trendno p-value reported

Compared with the AD group, the AD+YAP group had slightly but not significantly milder skin lesions, lower dermatitis scores, decreased ear swelling, and skin lesion thickness, while the AD+sh-YAP group had more severe skin lesions, increased dermatitis scores, increased degree of ear swelling, and an increasing trend in skin lesion thickness.

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