A multicenter study on the prognostic value of prednisone response in pediatric acute lymphoblastic leukemia.

Ann Hematol · 2025 · PMC12672685 · PMID 41071293

Europe PMC DOI

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0.1480

closest p · 3.0× alpha

0.1480

boldest claim

The sentences

failed to reach statistical significanceP = 0.148not close (p > 0.1)

In a multivariate analysis accounting for additional factors, the predictive capacity of prednisone response failed to reach statistical significance (HR 1.31, 95%CI 0.91–1.90; P = 0.148; Fig. 4 ).

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an overall trendno p-value reported

Survival analysis revealed that while statistical significance was not attained ( P > 0.05) in the D15 MRD ≥ 0.1% and D33 MRD < 0.01% subgroups, children in the PPR group exhibited an overall trend towards a poorer prognosis.

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