Oligocentric Castleman disease: clinical characteristics and surgical outcomes from a single-centre retrospective study.

Front Immunol · 2025 · PMC12672862 · PMID 41346625

Europe PMC DOI

hedged sentences

0.1050

closest p · 2.1× alpha

0.1050

boldest claim

The sentences

did not reach statistical significanceP = 0.105not close (p > 0.1)

Notably, all four PC-CD cases in the cohort were found within the high-inflammatory group, although this specific comparison did not reach statistical significance (P = 0.105) ( Table 5 ).

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highly significantno p-value reported

Specifically, non-contiguous nodal involvement(COINR Non-contiguous) (HR 20.9; 95% CI 3.92–112; P < 0.001), and the involvement of three or more nodal regions(NOIOR≥3) (HR 11.4; 95% CI 1.37–95.3; P = 0.024) were all highly significant predictors of a shorter PFS ( Table 3 , Figure 3e ).

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