Metabolomic changes associated with treatment response of neoadjuvant chemotherapy with TEC regimen in HER2-negative breast cancer.

Front Pharmacol · 2025 · PMC12673219 · PMID 41347169

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a decreasing trendno p-value reported

did not reach statistical significanceno p-value reported

Valine showed a decreasing trend at mid-treatment (T2) but rebounded to significantly elevated levels post-treatment (T3), while glycerophosphorylcholine levels tended to decrease post-NAC compared to baseline, these changes did not reach statistical significance.

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