Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.

Front Pharmacol · 2025 · PMC12676024 · PMID 41357894

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0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

borderline significantp < 0.00001actually significant

The effect of IL-5 changed from borderline significant to significantly negative (p < 0.00001) and the heterogeneity decreased (I 2 = 49%) ( Figure 9 ).

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did not reach statistical significanceno p-value reported

Neutrophil counts and IL-5 levels—a cytokine critical for eosinophil maturation and recruitment ( Cruz et al., 2008 )—displayed downward trends but did not reach statistical significance.

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