Resolving inflammation: The impact of antiretroviral therapy on macrophage traffic in and out of the CNS.

PLoS Pathog · 2025 · PMC12677798 · PMID 41325462

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did not reach statistical significanceno p-value reported

Following ART interruption, there is a 1.5-fold increase in the number of meningeal macrophages compared to ART that did not reach statistical significance and no increase in the number of choroid plexus macrophages (meninges ART: 54 ± 3.3 CD163 + /mm 2 ; ART Off: 70 ± 5.5 CD163 + /mm 2 ) (choroid plexus ART: 246 ± 192 CD68 + /mm 2 ; ART Off: 293 ± 167 CD68 + /mm 2 ) ( Fig 2B - C ).

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