In the Firth-penalized Cox regression analysis for DFS, patients with DLL3-high expression had a significantly increased risk of relapse compared with the DLL3-null group (HR 7.96; 95% CI 1.0–1029; p = 0.05), while DLL3-low expression did not reach statistical significance (Fig. 1 a).
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Multi-center Assessment of DLL3 Expression by Immunohistochemistry in Medullary Thyroid Carcinoma.
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