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Efficacy of luseogliflozin for renal function preservation in patients with type 2 diabetes mellitus and impaired renal function: A randomized open-label clinical trial (RESOLUTION study).

J Diabetes Investig · 2025 · PMC12679181 · PMID 41065037

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Conclusions Although the primary endpoint did not reach statistical significance, l useogliflozin may provide renoprotective benefits in patients with type 2 diabetes mellitus and moderate‐to‐severe renal impairment, potentially by slowing eGFRcreat decline post‐initial decline.

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