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Influenza Immunization at Midlife and the Risk of Parkinson Disease.

JAMA Netw Open · 2025 · PMC12681034 · PMID 41348356

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3 , 10 For example, a case-control study based on Danish data spanning several decades assessed the association between “any influenza infection prior to PD” and the risk of PD; the study showed a numerical increase that did not reach statistical significance (odds ratio [OR], 1.28; 95% CI, 0.91-1.82). 10 However, when stratifying based on time since infection, the Danish study showed that the increase in the risk of PD reached statistical significance 10 years after the infection (OR, 1.73; 95% CI, 1.11-2.71) and reached its peak magnitude 15 years after the infection (OR, 1.91; 95% CI, 1.14-3.19).

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