Association Between Oxidative Balance Score and Gynecological Cancer Using NHANES 2011-2018 Data.

Although the association with dietary OBS was modest and borderline significant in the highest tertile (OR = 0.77; 95% CI: 0.55–1.09), lifestyle OBS showed a stronger and independent inverse association with GC (OR per unit increase = 0.89; 95% CI: 0.83–0.96; highest vs lowest tertile OR = 0.64; 95% CI: 0.45–0.92).

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Slattery et al (2013) examined the dietary oxidative balance and observed a significant trend toward reduced breast cancer risk with a higher dietary oxidative balance. 18 Xu et al (2025) analyzed US cancer survivors and found that a higher OBS strongly predicted lower all-cause and cancer-specific mortality, 19 suggesting that even after diagnosis, better oxidative balance confers a survival advantage.

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