Siglec-8 as a Biomarker for Predicting Anti-IL-5 Response in Severe Asthma.

Allergy Asthma Immunol Res · 2025 · PMC12683740 · PMID 41330705

Europe PMC DOI

hedged sentences

0.0820

closest p · 1.6× alpha

0.0820

boldest claim

The sentences

a trend toward significanceP = 0.082so close (0.05 < p ≤ 0.1)

The improvement in diagnostic performance showed a trend toward significance only for predicting 6-month responders ( P = 0.082; Table 3 ).

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showed a trendno p-value reported

Baseline serum Siglec-8 levels showed a trend toward better diagnostic performance compared to blood eosinophil counts for predicting 6- and 12-month clinical responses (area under the curve, 0.931 vs. 0.836; P = 0.08 for 6-month responders; and 0.811 vs. 0.628, P = 0.05 for 12-month excellent responders).

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