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Efficacy based on dose-response and safety of bone marrow-derived mesenchymal stem cells for the treatment of osteoarthritis: a systematic review and meta-analysis.

Stem Cell Res Ther · 2025 · PMC12683818 · PMID 41361483

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The WOMAC-Function score also showed a non-significant improvement at most time points, however, a significant decrease in the function score was reported at 12 months, which, although statistically at the threshold of significance, from a clinical perspective indicates an improvement in functional independence and a decrease in motor disability of patients.

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