Barely Significant
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at the threshold of significance

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In the literature

at the threshold of significancep < 5.0 × 10 −80.0× alpha
Genetic Instrumental Variables for the Causal Association of Cataract with Glaucoma or AMD Twenty-eight IVs at the threshold of significance ( p < 5.0 × 10 −8 ) were chosen for cataract as exposure and glaucoma as outcome in multi-ethnic populations ( Table 2 ).
As for MRI brain structures, the negative association between baseline levels of CSF YKL-40 and entorhinal cortex volume was at the threshold of significance (β = −0.128, p = 0.049), but did not remain significant following FDR correction.
Similarly, when OS was considered, statistically significant differences for T2WI, DWI, and MR consensus were observed, with PET/MR consensus lying at the threshold of significance ( p = 0.05).
Notably, when treating baseline BMI as a continuous moderator, we observed a borderline trend at the threshold of significance ( p = 0.05; Supplementary Figure S1 ), indicating that lower baseline BMI is associated with greater reductions in BMI in response to LV-HIIT.
Associations between BMI and CSF AD core biomarkers and cognitive function In all participants, MLR models showed that continuous BMI variables were negatively correlated with the concentration of CSF P-tau (β = −0.29, p = 3.76 × 10 −5 ), T-tau (β = −2.51, p = 8.53 × 10 −5 ), P-tau/Aβ 42 (β = −6.51 × 10 −4 , p = 3.39 × 10 −6 ), and T-tau/Aβ 42 (β = −5.60 × 10 −3 , p = 2.71 × 10 −6 ), but the positive association with CSF Aβ 42 was at the threshold of significance (β = 6.31, p = 0.059) after controlling for aforementioned covariates ( Figure 2 and Supplemental Table 2A ).