A Behavioral Activation Digital Intervention Incorporating Gamification and Peer Support for Adolescent Depression in Rural South Africa: A Pilot Randomized Controlled Trial (the DoBAt Study).

Although we did not observe any between-group difference at our primary endpoint (adjusted mean difference [AMD] = −0.40, CI = −3.56, 2.75, Cohen d = −0.01), there was a nonsignificant trend favoring the treatment group at the 24-week follow-up (AMD = −1.62, CI = −4.76, 1.51, Cohen d = −0.25).

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However, although there are some indications of greater improvement in PHQ-A scores in the treatment group compared to the control group, the differences observed did not reach statistical significance across primary and secondary outcomes.

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