Endothelial dysfunction and proinflammatory state determine severe hematotoxicity and inferior outcome of CAR-T therapy.

Hemasphere · 2025 · PMC12684805 · PMID 41368079

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0.1500

closest p · 3.0× alpha

0.1500

boldest claim

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showed a trendP = 0.15not close (p > 0.1)

However, ide‐cel patients with high baseline sVCAM‐1 or sIL‐2R showed a trend towards worse PFS (P = 0.15; P = 0.17) (Figure S7G,J ).

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