Mayo Endoscopic Subscore at Week 24 Is a Predictor of Future Loss of Response to Vedolizumab in Patients with Ulcerative Colitis in Clinical Remission.

Inflamm Intest Dis · 2025 · PMC12685341 · PMID 41368124

Europe PMC DOI

hedged sentence

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

did not reach statistical significancep = 0.056so close (0.05 < p ≤ 0.1)

Furthermore, when comparing MES 0 and MES 1, the difference did not reach statistical significance ( p = 0.056); however, the numerical trend suggests a potential clinically relevant distinction that our study may have been underpowered to detect.

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