Development and Characterization of a Tunable PDMS Substrate Model for Investigating Elastic Properties and Mechanical Stretching in Intervertebral Disc Cells.

Although Donors 2 and 3 showed similar trends, stiffness‐dependent patterns were less consistent: Donor 2 showed a slight significance in low (840.0 ± 399.1 μm 2 ) compared to both, mid (710.1 ± 330.7 μm 2 , p < 0.01) and high (739.7 ± 290.2 μm 2 , p < 0.01) substrates, while Donor 3 showed significant differences between low and high formulations ( p < 0.01). 3.4 Strain Characterization of Stretching Chambers Under Mechanical Loading Using DIC Custom PDMS stretching chambers with integrated stiffness were fabricated using the developed aluminum mold.

also in 66 other papers