Association of Epigenetic Age Acceleration and Mitochondrial DNA-Based Aging Metrics Provides Insights Into Mechanisms of Aging-Related Diseases.

For other EAAs, including EAAHorvath, EAAHannum, EAAPheno, and DunedinPACE, higher MSS was associated with greater EAA levels in both females and males, although some of these associations did not reach statistical significance (Figure S2 ). 3.2.3 Associations Between Common Heteroplasmic Variant Burden Score and EAAs MH com count was calculated based on 39 common heteroplasmic variants (Gupta et al. 2023 ).

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