29 The lead SNP, rs35873421, showed a nominally significant association with ABCG1 expression in peripheral blood, while the second independent SNP, rs3787986, exhibited a strong association, with the alternate T allele linked to higher ABCG1 expression ( Z score = +5.7). 29 Additionally, 11 suggestive SNPs ( p < 1 × 10 −5 ) in high LD (r 2 > 0.9) with rs3787986 were also associated with increased ABCG1 expression ( Table S3 ).
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Genome-wide association study identifies <i>ABCG1</i> as a susceptibility locus for tick-borne encephalitis.
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