Barely Significant
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Cardiovascular degeneration in Erdheim-Chester disease: prevalence, burden, and outcomes.

Blood Adv · 2025 · PMC12686793 · PMID 40875593

1
hedged sentence
0.2800
closest p · 5.6× alpha
0.2800
boldest claim

The sentences

did not reach statistical significanceP = .28not close (p > 0.1)
Among the patients with ECD-C with a BRAF mutation, there was a trend toward improved PFS in those treated with targeted therapy; however, this difference did not reach statistical significance ( P = .28; supplemental Figure 1 ).

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